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Recurrent Miscarriages
August 2003

Q. I have had a total of four miscarriages. Through my workups I have found that I was factor 5 Liden positive, for which I take a daily children's aspirin. Otherwise, I'm pretty healthy. I had my first miscarriage at 6 weeks then a successful uneventful pregnancy-- my son is now 3 1/2.

We've been trying for a second child for the past few years. I have had three consecutive miscarriages. Two have been chemical miscarriages and the third was at 10 weeks. I have found no information on immunoglobulin treatment for recurrent miscarriage. Any insights on the subject?

A. Recurrent miscarriage is defined as 3 consecutive miscarriages which occur before 20 weeks gestation. A single miscarriage will occur in about 15% of known pregnancies, so the odds of three consecutive occurrences is quite low.

There are many possible causes but in the majority of cases no single cause can be identified. Despite this, 60-70% of affected women will have a subsequent successful pregnancy. Specific treatment depends on any causative factors that are found.

Examples would include chronic disease conditions, blood clotting disorders, uterine abnormalities, polycystic ovary syndrome, and others. Consult your doctor as to whether diagnostic testing is indicated in your situation.



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