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Mega-Ureter and Kidney Infection
March 2001

Q. I have congenital mega-ureter and suffer from frequent kidney infections. I was told that it is something that I would have to live with. Is there something that can be done about this? I don't want to be on antibiotics for the rest of my life. I am 38 years old and this was just diagnosed three years ago. I have suffered from kidney infections most of my life. I was just wondering if there is a procedure that would help correct this. The infection are more frequent now at approximately. every three to four months. Any advise you could give me would be greatly appreciated.

A. Megaureter is a congenital condition in which part of the ureter, the tube connecting the kidney to the bladder, fails to develop normally. Specifically, the muscle surrounding the ureter fails to develop which impairs the kidney's ability to empty properly, and can allow a backflow of urine from the bladder to the kidney. These abnormalities of anatomy and function cause infections of the urinary system to occur.

The cause of the condition is unknown, males are more commonly affected, and the condition usually involves one kidney, not both. In addition to treating infection, the goal is to preserve normal kidney function. Various surgical treatments are available to attempt to correct the anatomic problem. Whether any of these would be helpful to you is an issue to discuss with your treating physicians.





Shokeir AA, Nijman RJ. Primary megaureter: current trends in diagnosis and treatment BJU Int. 2000 Nov;86(7):861-8.

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