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Ask the Medical Expert Archives 2000-2004

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COX-2 Inhibitors
February 2000

Q. What are the risks of administering cox-2 inhibitors to cardiac patients?

A.The COX-2 inhibitors are a new class of anti-inflammatory medicine that have been designed to help patients who have a history of peptic ulcer disease. Most anti-inflammatory medicines are actually contraindicated in those with a history of a peptic ulcer because the medication can cause an ulcer. Not a lot is known about the COX-2 inhibitors since the medications are so new, having just come out in 1999. Still, they appear to be safe for those with cardiac disease, and some are even safe for patients taking Coumadin (a medicine often used with cardiac patients and a medicine that is known to have a lot of interaction with other medications).

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