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Ask the Medical Expert Archives 2000-2004

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Synthetic Thyroid
November 2000

Q. How important is it to take synthroid on an empty stomach?

A. Synthetic thyroid hormone is frequently used for treatment of various thyroid disorders, most commonly, for hypothyroidism (under active thyroid). The absorption of Synthroid is affected by certain substances including Iron, certain antacids and soybean formula. Although Synthroid is best absorbed in the fasting state (on an empty stomach), the fact of matter is that as long as you take it the same way each day, the dose will be titrated by your doctor via a blood test (TSH) so that you are on an effective (and therefore an adequately absorbed dose). Therefore, it is not critical that you be fasting when taking your usual daily dose.

Ref: Physicians Desk Reference 2000.

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